Carbapenemases - are you reviewing your laboratory procedures?

PHE AMRHAI - APRIL 2014

RAPID diagnostics are essential for identifying infected / colonized patients contributing to:

1. Appropriate patient management

2. Rapid implementation of infection control procedures

3. Prevent onwards transmission

Traditional sensitivity test methods are too slow for this purpose

UK SMI P08 - May 2014

'As a general principle, front-line diagnostic methods must have high sensitivity even at the expense of specificity'

'A simple 'Yes or No' result is sufficient for most diagnostic laboratories and infection prevention and control teams'

98022_rapid_esbl_test_150

Rosco's Rapid Carb is a 'here and now' product that significantly improves the rapid front-line screening needed to combat the threat of carbapenemases.

Rosco's Rapid Carb has been shown to detect carbapenemases with a high degree of sensitivity within 2 hours from initial plate culture, blood culture or urine.

Rapid Carb is easy to implement, being inexpensive and instrument independent.

Quotations from evaluations:

'The detection time of the carbapenemase producing isolates was reduced by >10 fold compared with standard methods'. Royal Free BSAC poster - Direct Detection of carbapenemase-producing Enterobacteriaceae and Pseudomonas spp. from positive blood cultures

'The Rapid Carb test was positive with 89 % of the Enterobacteriaceae,94%of K. pneumoniae carrying blaNDM and blaKPC gave a clearly positive result, more than half within 30min.' Royal London ECCMID poster - Evaluation of the Rapid Carb Test for the detection of Carbapenemase production in Gram negative bacteria

Rapid Carb is a front-line screen. Organisms giving a positive result or those with an antibiogram indicating possibility of a carbapenemase should be tested further.

98021, Rapid Carb Screen product page

98024, Neo-Rapid Carb Screen product page

Rosco Antibiotic Resistance Mechanism (ARM) detection kits product page