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Eazyplex Pneumobug

In humans, Chlamydophila pneumoniae commonly causes respiratory infections, widespread throughout the world. Seroepidemiological studies have concluded rising and high prevalence rates, with documented cases beginning in young children, increasing to 30-45% by adolescence [1]. Furthermore, this was seen to increase to >80% in some adult populations, with a high variance in C. pneumoniae-associated infection (0-44%) correlating to geographical location.  The mode of transmission for C. pneumoniae remains relatively unknown, but it has been suggested that transmission occurs via infected respiratory secretions [1].

However, an analysis consisting of comprehensive international databases found that the incidence of CAP resulting from C. pneumoniae from a sample size consisting of 4,337 patients was 7% in Europe (8% North America, 6% Latin America & 5% Asia) [2]. Developing on this, in 1998 a review was published with the findings that most reports ranked C. pneumoniae among the three most common etiologic agents of community-acquired pneumonia, with an incidence rate varying from 6-25% [3].

References:

  1. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7173483/
  2. https://emedicine.medscape.com/article/297351-overview?form=fpf#a3
  3. https://pubmed.ncbi.nlm.nih.gov/11869264/